Juvenile Onset OCD as a Meaningful Developmental Subtype
McLean Hospital
Daniel A. Geller, M.D., Noreen Zaman, B.A., Colleen Farrell, B.S., and Benjamin Mullin, B.A.
This study is a naturalistic family study that aims at distinguishing the differences and similarities of child and adolescent OCD and adult OCD in order to determine if the two are distinct disorders. A study that involves all family members allows us to gain information regarding trends in the family environment that we suspect would be distinctly different, if juvenile and adult onset OCD are, in fact, two different disorders. This study involves completing a diagnostic structured interview and cognitive/neurpsychological testing with each family member. We are currently in our third year of recruiting and have enrolled more than 80 families. By then end of this study in early 2004, we will have conducted interviews and cognitive testing with 100 juvenile probands (6-17 years old), 50 adults probands (> 20 years old) with juvenile onset, and 50 adult probands with adult onset.
Keywords: Obsessive-Compulsive Disorder (OCD), family study, naturalistic
Grant Support: NIMH 1 K08 MH01481-01A2 "Juvenile-Onset Obsessive Compulsive Disorder as a Meaningful Developmental Subtype"
Project Sites: McLean Hospital
Project Director: Daniel Geller, 115 Mill Street, Belmont, MA 02478
Contact Person: Colleen Farrell or Benjamin Mullin, Study Coordinators. Voicemail (617) 855-2861. Fax (617) 855-3691.
Representative Publications:
Geller D, Biederman J, Jones J, Park K, Schwartz S, Shapiro S, Coffey B. Is Juvenile Obsessive Compulsive Disorder a Developmental Subtype of the Disorder?: A Review of the Pediatric Literature. Journal of the American Academy of Child and Adolescent Psychiatry 1998;37:420-7.
Geller D, Biederman J, Faraone S, Frazier J, Coffey B, Kim G, Bellordre C. Clinical Correlates of Obsessive Compulsive Disorder in Children and Adolescents Referred to Specialized and Non-Specialized Clinical Settings. Depression and Anxiety 2000; 11(4) 163-168.
Geller D, Biederman J., Faraone, S.V., Bellordre, C.A., Kim, G.S., Hagermoser, L.H. Disentangling Chronological Age from Age of Onset in Children and Adolescents with Obsessive Compulsive Disorder. International Journal of Neuropsychopharmacology. 2001; 4: 169-178.
Geller D, Biederman J, Faraone S, Cradock K, Hagermoser L, Zaman N, Frazier J, Coffey B, Spencer T. Attention Deficit Hyperactivity Disorder in Children and Adolescents with Obsessive Compulsive Disorder: Fact or Artifact? Journal of the American Academy of Child and Adolescent Psychiatry. Accepted for publication.