CLINICAL STUDIES IN PATIENTS WITH SUBSTANCE USE DISORDERS
Alcohol and Drug Abuse Treatment Program, McLean Hospital
Roger D. Weiss, M.D., Shelly F. Greenfield, M.D., Lisa M. Najavits, Ph.D., Margaret L. Griffin, Ph.D., Jennifer Sharpe Potter, M.P.H., Grace O'Leary, M.D., Alisa Busch, M.D., Monika Kolodziej, Ph.D.
The purpose of this series of projects is to study clinical characteristics of patients with substance use disorders, with particular emphasis on the study of existing treatments and the development of new treatments for substance dependent patients. Specific studies involved in this project include studying combinations of pharmacotherapy and psychotherapy in the treatment of patients with alcohol dependence; new treatment approaches for individuals with bipolar disorder and substance use disorder and women with substance use disorders and post-traumatic stress disorder; gender differences in recovery from substance dependence; health services studies of patients with substance use disorders and psychiatric illness; and studies of self-help group utilization in substance dependent patients.
Key Words: substance use disorders, cocaine, drug dependence, alcoholism, treatment.
Grant Support: NIDA: R01 DA09400, A Relapse Prevention Group for Bipolar Substance Abusers (RDW); NIAAA: U10 AA11756, Behavioral and Pharmacologic Treatment of Alcoholism; NIDA: R01 DA12849, Genetics of Cocaine Dependence; R01 DA08631, Group Cognitive-Behavior Therapy and Dual Diagnosis Women (LMN); NIAAA: R21 AA12181, Cognitive-Behavior Therapy for PTSD/AUD Adolescent Girls (LMN); Dr. Ralph and Marian C. Falk Medical Research Trust (RDW).
Program Sites: Department of Psychiatry: Alcohol and Drug Abuse Treatment Program, McLean Hospital; Massachusetts General Hospital Addiction Services.
Program Director: Roger D. Weiss, M.D., McLean Hospital, 115 Mill Street, Belmont, MA 02478.
Contact Person: Roger D. Weiss, M.D., Tel. (617) 855-2242. Fax. (617) 855-2699. Email: weissr@mcleanpo.mclean.org
Training Opportunities: There will likely be an opening for one or two post-doctoral fellows.
Representative Publications:
Greenfield SF, Weiss RD, Muenz LR, Vagge LM, Kelly JF, Bello LR, Michael J. The effect of depression on return to drinking: a prospective study. Arch. Gen. Psychiatry 1998; 55:259-265.
Weiss RD, Greenfield SF, Najavits LM, Soto JA, Wyner D, Tohen M, Griffin ML. Medication compliance among patients with bipolar disorder and substance use disorder. J. Clin. Psychiatry 1998; 59:172-174.
Weiss RD, Griffin ML, Greenfield SF, Najavits LM, Wyner D, Soto JA, Hennen JA. Group therapy for patients with bipolar disorder and substance dependence: results of a pilot study. J Clin Psychiatry 2000; 61:361-367.
Weiss RD, Griffin ML, Gallop R, Luborsky L, Siqueland L, Frank A, Onken LS, Daley DC, Gastfriend DR. Predictors of self-help group attendance in cocaine dependent patients. J Stud Alcohol 2000; 61:714-719.
Najavits LM, Weiss RD, Shaw SR, Muenz LR. "Seeking safety:" outcome of a new cognitive-behavioral psychotherapy for women with posttraumatic stress disorder and substance dependence. J. Traumatic Stress 1998; 11:437-456.